GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| UCEC | cis | rs60843830 | 1 | rs57542652 | chr2:228088 | SH3YL1 | chr2:218138-264810:- | -0.45 | -5.56 | 1.18E-7 | Spherical equivalent (joint main effects and education interaction) |
| UCEC | cis | rs60843830 | 1 | rs58461606 | chr2:267367 | SH3YL1 | chr2:218138-264810:- | -0.5 | -6.7 | 3.85E-10 | Spherical equivalent (joint main effects and education interaction) |
| UCEC | cis | rs9309473 | 1 | rs58603761 | chr2:73726605 | ALMS1P | chr2:73872046-73912692:+ | 0.54 | 6.51 | 1.06E-9 | Metabolite levels |
| UCEC | cis | rs11880706 | 1 | rs59907625 | chr19:6079598 | ZNF557 | chr19:7069471-7087976:+ | 0.66 | 4.48 | 1.47E-5 | Bipolar disorder and schizophrenia |
| UCEC | cis | rs60843830 | 1 | rs59937473 | chr2:271797 | SH3YL1 | chr2:218138-264810:- | -0.43 | -6.02 | 1.28E-8 | Spherical equivalent (joint main effects and education interaction) |
| UCEC | cis | rs1930961 | 1 | rs6004673 | chr22:25885353 | CRYBB2 | chr22:25615612-25627836:+ | 0.57 | 4.92 | 2.25E-6 | Bipolar disorder with mood-incongruent psychosis |
| UCEC | cis | rs60843830 | 1 | rs60149603 | chr2:285421 | SH3YL1 | chr2:218138-264810:- | -0.49 | -6.68 | 4.23E-10 | Spherical equivalent (joint main effects and education interaction) |
| UCEC | cis | rs6028 | 1 | rs6028 | chr1:169551682 | F5 | chr1:169481192-169555769:- | -0.35 | -4.53 | 1.21E-5 | Activated partial thromboplastin time |
| UCEC | cis | rs965469 | 1 | rs6037583 | chr20:3360632 | ITPA | chr20:3190056-3204504:+ | -0.43 | -4.64 | 7.49E-6 | IFN-related cytopenia |
| UCEC | cis | rs60843830 | 1 | rs60484953 | chr2:221560 | SH3YL1 | chr2:218138-264810:- | -0.49 | -6.55 | 8.32E-10 | Spherical equivalent (joint main effects and education interaction) |
| UCEC | cis | rs965469 | 1 | rs6051708 | chr20:3262493 | ITPA | chr20:3190056-3204504:+ | -0.44 | -4.73 | 5.14E-6 | IFN-related cytopenia |
| UCEC | cis | rs965469 | 1 | rs6051764 | chr20:3321807 | ITPA | chr20:3190056-3204504:+ | 0.39 | 4.45 | 1.64E-5 | IFN-related cytopenia |
| UCEC | cis | rs965469 | 1 | rs6051779 | chr20:3333449 | ITPA | chr20:3190056-3204504:+ | -0.43 | -4.63 | 7.63E-6 | IFN-related cytopenia |
| UCEC | cis | rs965469 | 1 | rs6051790 | chr20:3342994 | ITPA | chr20:3190056-3204504:+ | -0.41 | -4.42 | 1.85E-5 | IFN-related cytopenia |
| UCEC | cis | rs965469 | 1 | rs6051792 | chr20:3343519 | ITPA | chr20:3190056-3204504:+ | -0.41 | -4.4 | 2.04E-5 | IFN-related cytopenia |